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From Houston: When going West on Interstate 10 from Houston, take the Pin Oak Rd. exit onto the feeder.  Stay on the feeder and go through the Pin Oak Rd. intersection.  Turn right on FM 1463 and the Merrell Center will be one block on the left.

From San Antonio: When going East on Interstate 10 from San Antonio, take the FM 1463 exit onto the feeder. Turn left onto FM 1463, going under the interstate, and the Merrell Center will be one block on the left.